Everything about Dissociation Chemistry totally explained
Dissociation in
chemistry and
biochemistry is a general process in which ionic compounds (
complexes,
molecules, or
salts) separate or split into smaller molecules, ions, or
radicals, usually in a reversible manner. When a
Bronsted-Lowry acid is put in water, a
covalent bond between an
electronegative atom and a hydrogen atom is broken by
heterolytic fission, which gives a proton and a negative
ion. Dissociation is the opposite of
association and
recombination. The process is frequently confused with
ionization.
Dissociation constant
For reversible dissociations in a
chemical equilibrium »
the
dissociation constant Kd is the ratio of dissociated to undissociated compound
»
Salts
The dissociation of salts by
solvation in a
solution like
water means the separation of the
anions and
cations. The salt can be recovered by
evaporation of the solvent. See also:
Solubility equilibrium
Acids
The dissociation of acids in a solution means the split-off of a
proton H
+, see
Acid-base reaction theories. This is an equilibrium process, meaning that dissociation and recombination takes place at the same time. The
acid dissociation constant Ka is an indicator of the acid strength: stronger acids have a higher
Ka value (and a lower p
Ka value).
Fragmentation
Fragmentation of a molecule can take place by a process of
heterolysis or
homolysis
Receptors
Receptors are
proteins that bind small
ligands. The dissociation constant
Kd is used as indicator of the
affinity of the ligand to the receptor. The higher the affinity of the ligand for the receptor the lower the
Kd value (and the higher the p
Kd value).
Further Information
Get more info on 'Dissociation Chemistry'.
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